SEPHS1 and IGSF21

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SEPHS1	IGSF21
Description		selenophosphate synthetase 1	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Nuclear Membrane	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	Selenide, Water Dikinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cellular Protein Modification Process Selenocysteine Biosynthetic Process Phosphorylation	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483)	Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		18 interacting genes: CDCA4 CRMP1 DEPDC7 ERG28 GBP2 IGSF21 PLAGL2 QRICH1 SAT1 SLC35F6 SPACA9 UNC119 XAF1 ZBTB25 ZNF202 ZNF276 ZNF474 ZNF526	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		22929	84966
HPRD ID		02944	11309
Ensembl ID		ENSG00000086475	ENSG00000117154
Uniprot IDs		P49903	Q96ID5
PDB IDs		3FD5 3FD6
Enriched GO Terms of Interacting Partners?
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