FKBP3 and MTA2

Data Source:
BioGRID (pull down)

		FKBP3	MTA2
Description		FKBP prolyl isomerase 3	metastasis associated 1 family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Membrane NuRD Complex Protein-containing Complex
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Signaling Receptor Activity	RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Histone Deacetylase Binding Sequence-specific DNA Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Assembly Or Disassembly Regulation Of Fibroblast Migration Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: BARD1 CALM1 CDC42 CSNK2A1 CSNK2A2 CSNK2B ERBB2 FBXO25 HDAC1 HDAC2 MTA2 NEDD4 NEDD4L SMURF1 SRPK1 YY1	23 interacting genes: APPL1 APPL2 BCL11B ERCC6 ESR1 FKBP3 H3-4 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN SUMO2 TP53 TSC22D3 UBE3C USP11 YY1
Entrez ID		2287	9219
HPRD ID		01743	07233
Ensembl ID		ENSG00000100442	ENSG00000149480
Uniprot IDs		Q00688	A0A024R534 O94776
PDB IDs		1PBK 2KFV 2MPH 5D75 5GPG
Enriched GO Terms of Interacting Partners?
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