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FHL2 and SFPQ
Data Source:
HPRD
(two hybrid)
FHL2
SFPQ
Description
four and a half LIM domains 2
splicing factor proline and glutamine rich
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Focal Adhesion
Z Disc
M Band
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
Nuclear Speck
Dendrite Cytoplasm
Paraspeckles
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Identical Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Nucleic Acid Binding
DNA Binding
Chromatin Binding
RNA Binding
Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Response To Hormone
Regulation Of Lipid Metabolic Process
Negative Regulation Of Apoptotic Process
Atrial Cardiac Muscle Cell Development
Ventricular Cardiac Muscle Cell Development
Heart Trabecula Formation
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Transcription By RNA Polymerase II
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Double-strand Break Repair Via Homologous Recombination
Activation Of Innate Immune Response
Regulation Of Transcription, DNA-templated
MRNA Processing
RNA Splicing
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Innate Immune Response
Positive Regulation Of Sister Chromatid Cohesion
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Histone H3 Deacetylation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
PPARA activates gene expression
PTK6 Regulates Proteins Involved in RNA Processing
Suppression of apoptosis
Drugs
Copper
Artenimol
Diseases
GWAS
Body fat mass (
28552196
)
Household income (MTAG) (
31844048
)
Lung cancer in ever smokers (
28604730
)
PR interval (
32439900
)
Pulse pressure (
30224653
30578418
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Endometrial cancer (
21499250
)
Hip circumference (
28552196
)
Interacting Genes
174 interacting genes:
A1CF
ABI1
ABLIM1
ADAM17
AK1
AKIP1
AMOT
ANKRD55
APP
AR
ARHGAP9
ATXN1
BANP
BARX2
BIN1
BLZF1
BMPR2
BRCA1
C20orf85
C2CD6
CAND2
CAPN1
CARD8
CCDC198
CCDC92
CKM
CREBBP
CSK
CSN2
CTNNB1
DAPL1
DCP1A
DDIT4L
DEAF1
DLGAP1
DPF2
DTX2
DUSP10
E2F1
E2F2
E2F3
E2F4
EP300
ESR1
FAM204A
FAM214B
FHL1
FHL3
FHL5
FOXO1
GAS8
GATAD2B
GLYR1
GMEB2
GNG12
GNG4
GOLGA6A
GTF2F2
GTF2H1
HAND1
HCK
HSF2BP
HSPB2
ID3
IDH1
IER3
IFI35
IGFBP5
IKZF1
IKZF4
IL16
INCA1
ITGA3
ITGA7
ITGB1
ITGB2
ITGB5
ITGB6
JUP
KANK2
KIAA1217
KIF5B
KLF12
KPRP
LDLRAP1
LRIF1
MAGEL2
MBD3L1
MCM7
MDM2
MISP
MYBPC1
MYO15B
NBPF6
NIBAN1
NRF1
PFKM
PHB2
PHF1
PHF21A
PKNOX1
PKNOX2
POGZ
POU6F2
PPP1R32
PRDM11
PRDM6
PRR5L
PSEN2
PUF60
QRICH1
RAI2
RASL12
REL
REV1
RFX3
RIPPLY1
RUNX2
SAP30BP
SAXO1
SAXO2
SCNM1
SFPQ
SH3RF1
SIGLEC6
SLAIN1
SLC34A1
SMAD2
SMAD3
SMAD4
SNAI1
SOX30
SP2
SPRY4
SREBF2
SRF
STAT3
SUMO1P1
TCP10L
TNFRSF11A
TOX3
TRAF6
TRIM55
TRIM63
TRIM73
TTN
TXNRD3
VXN
WASHC1
WT1
YPEL3
YY1
ZBTB16
ZBTB25
ZFP64
ZFYVE9
ZMYM4
ZNF131
ZNF143
ZNF200
ZNF212
ZNF23
ZNF3
ZNF331
ZNF408
ZNF410
ZNF417
ZNF620
ZNF626
ZNF638
ZNF655
ZNF76
ZNF85
ZSCAN9
103 interacting genes:
APBB1
AR
CSNK2A1
ERG
ESR1
EXOSC5
FHL2
FUS
GAS7
H3-4
JPT1
LAMTOR5
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NONO
PIN1
PPARG
PPP1CA
PRPF40A
PSPC1
PTBP1
RAC1
SIN3A
SMAD5
SNRPA
SREK1
TCERG1
TOP1
UBC
UBE2I
WBP4
ZMYM2
Entrez ID
2274
6421
HPRD ID
04026
07284
Ensembl ID
ENSG00000115641
ENSG00000116560
Uniprot IDs
Q14192
Q2XQU9
Q6I9R8
A0A384N5Z8
P23246
Q86VG2
PDB IDs
1X4K
1X4L
2D8Z
2MIU
4WII
4WIJ
4WIK
5WPA
6NCQ
6OWJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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