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FHL2 and DEAF1
Data Source:
BioGRID
(two hybrid)
FHL2
DEAF1
Description
four and a half LIM domains 2
DEAF1 transcription factor
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Focal Adhesion
Z Disc
M Band
Chromatin
Fibrillar Center
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Identical Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Response To Hormone
Regulation Of Lipid Metabolic Process
Negative Regulation Of Apoptotic Process
Atrial Cardiac Muscle Cell Development
Ventricular Cardiac Muscle Cell Development
Heart Trabecula Formation
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Transcription By RNA Polymerase II
Neural Tube Closure
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Germ Cell Development
Anatomical Structure Morphogenesis
Regulation Of Mammary Gland Epithelial Cell Proliferation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Embryonic Skeletal System Development
Pathways
PPARA activates gene expression
Drugs
Diseases
GWAS
Body fat mass (
28552196
)
Household income (MTAG) (
31844048
)
Lung cancer in ever smokers (
28604730
)
PR interval (
32439900
)
Pulse pressure (
30224653
30578418
)
Interacting Genes
174 interacting genes:
A1CF
ABI1
ABLIM1
ADAM17
AK1
AKIP1
AMOT
ANKRD55
APP
AR
ARHGAP9
ATXN1
BANP
BARX2
BIN1
BLZF1
BMPR2
BRCA1
C20orf85
C2CD6
CAND2
CAPN1
CARD8
CCDC198
CCDC92
CKM
CREBBP
CSK
CSN2
CTNNB1
DAPL1
DCP1A
DDIT4L
DEAF1
DLGAP1
DPF2
DTX2
DUSP10
E2F1
E2F2
E2F3
E2F4
EP300
ESR1
FAM204A
FAM214B
FHL1
FHL3
FHL5
FOXO1
GAS8
GATAD2B
GLYR1
GMEB2
GNG12
GNG4
GOLGA6A
GTF2F2
GTF2H1
HAND1
HCK
HSF2BP
HSPB2
ID3
IDH1
IER3
IFI35
IGFBP5
IKZF1
IKZF4
IL16
INCA1
ITGA3
ITGA7
ITGB1
ITGB2
ITGB5
ITGB6
JUP
KANK2
KIAA1217
KIF5B
KLF12
KPRP
LDLRAP1
LRIF1
MAGEL2
MBD3L1
MCM7
MDM2
MISP
MYBPC1
MYO15B
NBPF6
NIBAN1
NRF1
PFKM
PHB2
PHF1
PHF21A
PKNOX1
PKNOX2
POGZ
POU6F2
PPP1R32
PRDM11
PRDM6
PRR5L
PSEN2
PUF60
QRICH1
RAI2
RASL12
REL
REV1
RFX3
RIPPLY1
RUNX2
SAP30BP
SAXO1
SAXO2
SCNM1
SFPQ
SH3RF1
SIGLEC6
SLAIN1
SLC34A1
SMAD2
SMAD3
SMAD4
SNAI1
SOX30
SP2
SPRY4
SREBF2
SRF
STAT3
SUMO1P1
TCP10L
TNFRSF11A
TOX3
TRAF6
TRIM55
TRIM63
TRIM73
TTN
TXNRD3
VXN
WASHC1
WT1
YPEL3
YY1
ZBTB16
ZBTB25
ZFP64
ZFYVE9
ZMYM4
ZNF131
ZNF143
ZNF200
ZNF212
ZNF23
ZNF3
ZNF331
ZNF408
ZNF410
ZNF417
ZNF620
ZNF626
ZNF638
ZNF655
ZNF76
ZNF85
ZSCAN9
20 interacting genes:
AIMP2
ASCC2
CDC37
CDKN1A
CDKN2A
CEP76
FHL1
FHL2
GSK3A
GSK3B
HRAS
INTS1
LMO4
PELI2
PIN1
PPP1CA
PPP1CC
RAD23B
RIDA
TK1
Entrez ID
2274
10522
HPRD ID
04026
04027
Ensembl ID
ENSG00000115641
ENSG00000177030
Uniprot IDs
Q14192
Q2XQU9
Q6I9R8
O75398
PDB IDs
1X4K
1X4L
2D8Z
2MIU
2JW6
4A24
5UWW
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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