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FHL2 and YY1
Data Source:
BioGRID
(two hybrid)
FHL2
YY1
Description
four and a half LIM domains 2
YY1 transcription factor
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Focal Adhesion
Z Disc
M Band
Nucleus
Nucleoplasm
Transcription Regulator Complex
Chromatin Silencing Complex
Cytoplasm
Nuclear Matrix
Ino80 Complex
PcG Protein Complex
Molecular Function
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Identical Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Four-way Junction DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
RNA Binding
Protein Binding
SMAD Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Response To Hormone
Regulation Of Lipid Metabolic Process
Negative Regulation Of Apoptotic Process
Atrial Cardiac Muscle Cell Development
Ventricular Cardiac Muscle Cell Development
Heart Trabecula Formation
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair Via Homologous Recombination
Regulation Of Transcription By RNA Polymerase II
RNA Localization
Cellular Response To DNA Damage Stimulus
Spermatogenesis
Anterior/posterior Pattern Specification
Response To UV-C
Negative Regulation Of Gene Expression
Protein Deubiquitination
B Cell Differentiation
Negative Regulation Of Interferon-beta Production
Cellular Response To UV
Response To Prostaglandin F
Positive Regulation Of Transcription By RNA Polymerase II
Cell Development
Camera-type Eye Morphogenesis
Chromosome Organization
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Interleukin-1
Immunoglobulin Heavy Chain V-D-J Recombination
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways
PPARA activates gene expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
UCH proteinases
DNA Damage Recognition in GG-NER
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Body fat mass (
28552196
)
Household income (MTAG) (
31844048
)
Lung cancer in ever smokers (
28604730
)
PR interval (
32439900
)
Pulse pressure (
30224653
30578418
)
Estimated glomerular filtration rate (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Pulse pressure (
30224653
)
Interacting Genes
174 interacting genes:
A1CF
ABI1
ABLIM1
ADAM17
AK1
AKIP1
AMOT
ANKRD55
APP
AR
ARHGAP9
ATXN1
BANP
BARX2
BIN1
BLZF1
BMPR2
BRCA1
C20orf85
C2CD6
CAND2
CAPN1
CARD8
CCDC198
CCDC92
CKM
CREBBP
CSK
CSN2
CTNNB1
DAPL1
DCP1A
DDIT4L
DEAF1
DLGAP1
DPF2
DTX2
DUSP10
E2F1
E2F2
E2F3
E2F4
EP300
ESR1
FAM204A
FAM214B
FHL1
FHL3
FHL5
FOXO1
GAS8
GATAD2B
GLYR1
GMEB2
GNG12
GNG4
GOLGA6A
GTF2F2
GTF2H1
HAND1
HCK
HSF2BP
HSPB2
ID3
IDH1
IER3
IFI35
IGFBP5
IKZF1
IKZF4
IL16
INCA1
ITGA3
ITGA7
ITGB1
ITGB2
ITGB5
ITGB6
JUP
KANK2
KIAA1217
KIF5B
KLF12
KPRP
LDLRAP1
LRIF1
MAGEL2
MBD3L1
MCM7
MDM2
MISP
MYBPC1
MYO15B
NBPF6
NIBAN1
NRF1
PFKM
PHB2
PHF1
PHF21A
PKNOX1
PKNOX2
POGZ
POU6F2
PPP1R32
PRDM11
PRDM6
PRR5L
PSEN2
PUF60
QRICH1
RAI2
RASL12
REL
REV1
RFX3
RIPPLY1
RUNX2
SAP30BP
SAXO1
SAXO2
SCNM1
SFPQ
SH3RF1
SIGLEC6
SLAIN1
SLC34A1
SMAD2
SMAD3
SMAD4
SNAI1
SOX30
SP2
SPRY4
SREBF2
SRF
STAT3
SUMO1P1
TCP10L
TNFRSF11A
TOX3
TRAF6
TRIM55
TRIM63
TRIM73
TTN
TXNRD3
VXN
WASHC1
WT1
YPEL3
YY1
ZBTB16
ZBTB25
ZFP64
ZFYVE9
ZMYM4
ZNF131
ZNF143
ZNF200
ZNF212
ZNF23
ZNF3
ZNF331
ZNF408
ZNF410
ZNF417
ZNF620
ZNF626
ZNF638
ZNF655
ZNF76
ZNF85
ZSCAN9
90 interacting genes:
ALOXE3
APP
ATF2
ATF6
ATF7
AURKA
BAP1
BCCIP
BRCA1
CDKN2A
CEP76
CREB1
CRKL
CYSRT1
DNMT3L
E2F2
E2F3
EED
EP300
ESM1
FHL2
FKBP1A
FKBP3
GMCL1
GRN
GTF2I
HCFC1
HDAC2
HDAC3
HOXA11
IL10
INO80
KAT2B
KRTAP1-3
KRTAP1-5
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-3
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP4-2
KRTAP4-5
KRTAP5-6
KRTAP9-3
KRTAP9-8
LHX3
LHX4
MDFI
MED20
MTA2
MYC
NEDD4L
NFKB1
NOTCH1
NPM1
NR1H2
PLEKHF2
PPIA
PSMD9
RAF1
RUVBL1
RUVBL2
RYBP
SAP30
SF3A2
SKP2
SLC39A7
SMAD1
SMAD2
SMAD3
SMURF2
SP1
SPRY1
SREBF1
TESK1
TFCP2
TP53
TRIM42
TWIST1
UHRF2
VWC2
XAGE1A
XAGE1B
YAF2
ZNF232
ZNF85
ZRANB2
Entrez ID
2274
7528
HPRD ID
04026
02482
Ensembl ID
ENSG00000115641
ENSG00000100811
Uniprot IDs
Q14192
Q2XQU9
Q6I9R8
P25490
PDB IDs
1X4K
1X4L
2D8Z
2MIU
1UBD
1ZNM
4C5I
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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