RBM17 and SF1

Data Source:
BioGRID (two hybrid)

		RBM17	SF1
Description		RNA binding motif protein 17	splicing factor 1
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Spliceosomal Complex Ribosome
	Molecular Function	RNA Binding Protein Binding	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Brooding (response to stress) ( 30886212) Crohn's disease ( 28067908) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 24076602) Soluble interleukin-2 receptor subunit alpha ( 26293465) Vitiligo ( 20410501)	Mean reticulocyte volume ( 32888494) Urate levels ( 21768215)
Interacting Genes		27 interacting genes: APBB1 CCDC170 CCHCR1 CEP55 CSNK2A1 CWC15 DHX15 FAM9B GOLGA2 HINFP HSF2BP IQCN LNX2 MIR106B MIR107 MIR128-1 MIR155 MIR21 MIR25 MIRLET7A2 MIRLET7G MIRLET7I PPP1R12C QRICH1 SAP30BP SAT1 SF1	58 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CDC42 CIAO1 DDX17 DUX4L9 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MIR106B MIR155 MIR19B2 MIR34A MIRLET7G MKRN3 NCK2 NFKB1 OSTF1 PLSCR1 PRKG1 PRPF40A PSMA3 PUF60 RBM10 RBM17 RBM4 RBM7 RBPMS SEC23A SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TNPO2 TRIM23 TRIM69 TTN TXNL4B U2AF2 UBL5 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		84991	7536
HPRD ID		09501	03306
Ensembl ID		ENSG00000134453	ENSG00000168066
Uniprot IDs		Q5W009 Q96I25	A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637
PDB IDs		2PE8 2PEH 5LSO 6HIP	1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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