FABP3 and VPS28

Data Source:
HPRD (two hybrid)

		FABP3	VPS28
Description		fatty acid binding protein 3	VPS28 subunit of ESCRT-I
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GO Annotations	Cellular Component	Extracellular Space Cytosol Sarcoplasm Extracellular Exosome	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome
	Molecular Function	Long-chain Fatty Acid Transporter Activity Protein Binding Cytoskeletal Protein Binding Long-chain Fatty Acid Binding Icosatetraenoic Acid Binding Oleic Acid Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Fatty Acid Metabolic Process Negative Regulation Of Cell Population Proliferation Long-chain Fatty Acid Transport Triglyceride Catabolic Process Intracellular Lipid Transport Response To Insulin Response To Drug Cholesterol Homeostasis Regulation Of Fatty Acid Oxidation Brown Fat Cell Differentiation Phospholipid Homeostasis Response To Fatty Acid Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Into Cell Regulation Of Phosphatidylcholine Biosynthetic Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Triglyceride catabolism	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		4 interacting genes: NUP62 SHTN1 TNNI3K VPS28	45 interacting genes: ABI2 ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52
Entrez ID		2170	51160
HPRD ID		00613	11675
Ensembl ID		ENSG00000121769	ENSG00000160948
Uniprot IDs		A0A384MDY5 P05413	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs		1G5W 1HMR 1HMS 1HMT 2HMB 3RSW 3WBG 3WVM 3WXQ 4TJZ 4TKB 4TKH 4TKJ 4WBK 5B27 5B28 5B29 5CE4 5HZ9 6AQ1	6VME
Enriched GO Terms of Interacting Partners?
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