VPS28 and GLCCI1

Data Source:
HPRD (in vivo, in vitro)

		VPS28	GLCCI1
Description		VPS28 subunit of ESCRT-I	glucocorticoid induced 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 24684796) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Height ( 28552196 31562340) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 23836780) Macular thickness ( 30535121) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		45 interacting genes: ABI2 ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52	1 interacting genes: VPS28
Entrez ID		51160	113263
HPRD ID		11675	17043
Ensembl ID		ENSG00000160948	ENSG00000106415
Uniprot IDs		A0A0S2Z5H5 Q548N1 Q9UK41	Q86VQ1
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?
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