VPS28 and BLZF1

Data Source:
BioGRID (two hybrid)

		VPS28	BLZF1
Description		VPS28 subunit of ESCRT-I	basic leucine zipper nuclear factor 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	Protein Binding Ubiquitin Binding Protein-containing Complex Binding	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding
	Biological Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis	Golgi Organization Golgi To Plasma Membrane Protein Transport
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Golgi Cisternae Pericentriolar Stack Reorganization
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		45 interacting genes: ABI2 ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52	101 interacting genes: AKAP9 AMOTL2 ANKS1A AQP1 BAG4 BANP BCL6 BEX2 CARD9 CCDC120 CCDC33 CCNH CDC37 CDK18 CFAP206 CHCHD3 CINP CKS2 CTNNA3 DNMT3L ENKD1 ERCC3 EWSR1 EXOC8 FAM124B FAM90A1 FBF1 FHL2 FRMD6 FRS3 GEM GORASP2 HCLS1 HDAC4 HOXA1 HOXC8 IGFN1 IKZF3 IL16 IQUB KANK2 KAT5 KCTD9 KDM1A KIF9 KLHL38 LGALS14 LMO1 LMO2 LMO3 LNX1 MID2 MISP MKRN3 NTAQ1 OAZ3 PCDHB12 PIK3R3 PKN1 POLR1C PRKAB2 PRMT6 PRPF18 PSMA1 PTPN11 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SMAD3 SMARCB1 SPRED1 SRA1 SSX2 SUV39H2 SYT17 TBC1D22B TBC1D7 TCAP TCF19 TEKT4 TNS2 TRAPPC2L TRIM59 TSC22D4 TSTD2 TTC23 TXNDC5 USHBP1 VPS28 ZBTB16 ZBTB24 ZGPAT ZMAT1 ZNF124 ZNF410 ZNF688 ZNF76 ZZZ3
Entrez ID		51160	8548
HPRD ID		11675	16367
Ensembl ID		ENSG00000160948	ENSG00000117475
Uniprot IDs		A0A0S2Z5H5 Q548N1 Q9UK41	Q9H2G9
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?
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