VPS28 and CEP57L1

Data Source:
BioGRID (two hybrid)

		VPS28	CEP57L1
Description		VPS28 subunit of ESCRT-I	centrosomal protein 57 like 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome	Cellular_component Cytoplasm Centrosome Microtubule
	Molecular Function	Protein Binding Ubiquitin Binding Protein-containing Complex Binding	Molecular_function Protein Binding Microtubule Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis	Biological_process
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Midgestational circulating levels of PCBs ( 28235828) Prostate cancer ( 23535732)
Interacting Genes		45 interacting genes: ABI2 ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52	84 interacting genes: AKT1 ALOX5 AP1M1 ARNT2 BRCA1 BYSL CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 CFAP206 DISC1 DVL3 DYDC1 ELOA EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 GRIPAP1 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO1 LMO3 LZTS2 MAGEA1 MAGEA2B MCC MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NEFL NOTCH1 NUP62 PATJ PICK1 PKN1 PNMA5 PPL PRDM6 RAD51D RINT1 ROPN1 SNAP47 SNAPC3 TAB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB VPS28 YES1 ZGPAT ZNF572 ZNF655
Entrez ID		51160	285753
HPRD ID		11675	10792
Ensembl ID		ENSG00000160948	ENSG00000183137
Uniprot IDs		A0A0S2Z5H5 Q548N1 Q9UK41	E5RFY4 Q8IYX8
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?
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