EXTL3 and PLEKHA5

Data Source:
BioGRID (two hybrid)

		EXTL3	PLEKHA5
Description		exostosin like glycosyltransferase 3	pleckstrin homology domain containing A5
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity Protein Binding Transferase Activity, Transferring Glycosyl Groups Metal Ion Binding	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Cell Growth IRE1-mediated Unfolded Protein Response	Biological_process Reproductive System Development
Pathways		XBP1(S) activates chaperone genes	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Height ( 25429064) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Moderate-to-late spontaneous preterm birth ( 31194736)	Adult body size ( 32376654) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)
Interacting Genes		2 interacting genes: ATXN1 PLEKHA5	31 interacting genes: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG
Entrez ID		2137	54477
HPRD ID		09306	09684
Ensembl ID		ENSG00000012232	ENSG00000052126
Uniprot IDs		A0A384NPY9 O43909	A0A024RAY7 Q9HAU0
PDB IDs			2DKP
Enriched GO Terms of Interacting Partners?
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