ERH and IGSF21

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERH	IGSF21
Description		ERH mRNA splicing and mitosis factor	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Midbody Methylosome	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	RNA Binding Protein Binding Methyl-CpG Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleoside Metabolic Process Cell Cycle	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)	Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		25 interacting genes: APP ATP6V0C CENPH CHTOP CIZ1 COPS6 CSNK2A1 CSNK2A2 CTDP1 CYSRT1 HSPA8 IFITM10 IGSF21 MED31 POLDIP3 PSMA6 RBM48 RPS6KA5 SETDB1 SH3GL2 TASOR2 TLE1 TP53 UNC119 UPRT	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		2079	84966
HPRD ID		09026	11309
Ensembl ID		ENSG00000100632	ENSG00000117154
Uniprot IDs		A0A024R6D4 P84090	Q96ID5
PDB IDs		1W9G 2NML 7CNC
Enriched GO Terms of Interacting Partners?
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