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TRIML2 and XAF1
Data Source:
BioGRID
(two hybrid)
TRIML2
XAF1
Description
tripartite motif family like 2
XIAP associated factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Nucleoplasm
Mitochondrion
Cytosol
Molecular Function
Protein Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Protein Binding
Zinc Ion Binding
Biological Process
Protein Polyubiquitination
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Response To Retinoic Acid
Regulation Of Protein Localization
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of NF-kappaB Transcription Factor Activity
Apoptotic Process
Response To Interferon-beta
Type I Interferon Signaling Pathway
Pathways
Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Polycystic ovary syndrome (
25574032
)
Interacting Genes
48 interacting genes:
ABI2
BLOC1S2
CBY2
CCDC146
CCDC92
CCHCR1
CCNH
CDR2
CTBP2
EIF2B1
EIF3M
FAM90A1
FAM9C
HGS
ING5
ITGB3BP
KRT15
KRT24
KRT27
KRT31
KRT34
KRT38
KRT75
MBD3L2
MBD3L3
MEOX1
MEOX2
NECAB2
NFKBID
NUP62
PICK1
POLR1H
POU6F2
SH2D4A
STN1
SUMO2
SYCE2
TBC1D25
TCF4
TFIP11
TRIM54
TSEN54
TSG101
USHBP1
XAF1
ZBED1
ZBTB33
ZFHX3
18 interacting genes:
AKT1
APP
BIRC7
CREBBP
GLS2
LRSAM1
RFC5
RNF114
RNF166
SEPHS1
TP53
TRIM21
TRIM50
TRIM54
TRIML2
UBXN2B
VCP
XIAP
Entrez ID
205860
54739
HPRD ID
08696
06978
Ensembl ID
ENSG00000179046
ENSG00000132530
Uniprot IDs
B7ZLC3
Q8N7C3
Q6GPH4
PDB IDs
2LXW
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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