XAF1 and LRSAM1

Data Source:
BioGRID (two hybrid)

		XAF1	LRSAM1
Description		XIAP associated factor 1	leucine rich repeat and sterile alpha motif containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway	Protein Polyubiquitination Autophagy Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis Positive Regulation Of Xenophagy Positive Regulation Of Autophagosome Assembly
Pathways		Interferon alpha/beta signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Mean corpuscular volume ( 32888494)
Interacting Genes		18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP	42 interacting genes: ATXN1 ATXN7 CCDC6 DMAP1 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MAGEA1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2I UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11 XAF1 ZMAT4
Entrez ID		54739	90678
HPRD ID		06978	14325
Ensembl ID		ENSG00000132530	ENSG00000148356
Uniprot IDs		Q6GPH4	A0A024R870 Q6UWE0
PDB IDs		2LXW
Enriched GO Terms of Interacting Partners?
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