TRIML2 and KRT24

Data Source:
BioGRID (two hybrid)

		TRIML2	KRT24
Description		tripartite motif family like 2	keratin 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Response To Retinoic Acid Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity	Biological_process Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		48 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCDC92 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZBTB33 ZFHX3	32 interacting genes: AARD ABI2 ABI3 AMOT BFSP2 C1orf109 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT20 KRT3 KRT4 KRT5 KRT6C KRT71 KRT72 KRT75 KRT79 KRT8 KRT80 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		205860	192666
HPRD ID		08696	09668
Ensembl ID		ENSG00000179046	ENSG00000167916
Uniprot IDs		B7ZLC3 Q8N7C3	Q2M2I5
PDB IDs
Enriched GO Terms of Interacting Partners?
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