VAMP3 and CLEC14A

Data Source:
BioGRID (two hybrid)

		VAMP3	CLEC14A
Description		vesicle associated membrane protein 3	C-type lectin domain containing 14A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane	External Side Of Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding	Protein Binding Carbohydrate Binding Extracellular Matrix Binding Extracellular Matrix Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Positive Regulation Of Immunoglobulin Production Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell	Lymphangiogenesis Cell Migration Involved In Sprouting Angiogenesis Cell Migration Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Vascular Endothelial Growth Factor Receptor-3 Signaling Pathway
Pathways		ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			Resveratrol
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)	Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Type 2 diabetes ( 30297969 32499647) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		63 interacting genes: ACAP1 AHNAK2 AIG1 APP AQP6 ARL13B BCAP31 BCL2L13 BIK BSCL2 BSND CD79A CIAO2A CLDN7 CLEC14A COMT DDB1 DNAJC5 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B GORAB GPX8 IKBKG KCNK5 LHFPL5 LMNA MGST2 MGST3 NELFE NEMP1 PDZK1IP1 PLEKHO1 PTGES RETREG3 RMDN3 SAR1A SCN3B SLC10A1 SLC16A2 SNAP23 SNAP29 STX16 STX1A STX2 STX3 STX4 TM4SF19 TM4SF20 TMEM237 TMEM31 TMEM35A TMEM52B TMEM86B TMPPE TMX2 VAMP2 VAMP8 VEGFD VSIR	13 interacting genes: ATP6V0C CLDN19 CLDN4 CYB561D2 EMD LHFPL5 MALL MGST2 MS4A1 PMP22 TMEM243 TSPAN2 VAMP3
Entrez ID		9341	161198
HPRD ID		04711	10711
Ensembl ID		ENSG00000049245	ENSG00000176435
Uniprot IDs		Q15836 Q6FGG2	Q86T13
PDB IDs
Enriched GO Terms of Interacting Partners?
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