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FCER1G and EBP
Data Source:
BioGRID
(two hybrid)
FCER1G
EBP
Description
Fc fragment of IgE receptor Ig
EBP cholestenol delta-isomerase
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Cytoplasmic Vesicle
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
C-8 Sterol Isomerase Activity
Steroid Delta-isomerase Activity
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Xenobiotic Transmembrane Transporter Activity
Cholestenol Delta-isomerase Activity
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Skeletal System Development
Cholesterol Biosynthetic Process
Cholesterol Metabolic Process
Sterol Biosynthetic Process
Cholesterol Biosynthetic Process Via Desmosterol
Cholesterol Biosynthetic Process Via Lathosterol
Xenobiotic Transport
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
Cholesterol biosynthesis via desmosterol
Cholesterol biosynthesis via lathosterol
Drugs
Benzylpenicilloyl polylysine
Tamoxifen
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Interacting Genes
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
171 interacting genes:
ABHD16A
ANKRD46
APP
AQP6
ARL13B
ARL6IP6
ARV1
ATP13A1
BMP10
BNIP3
BTN2A2
C2
C2CD2L
C4orf3
C5
C5orf46
CCDC167
CCL4L2
CD40
CD69
CD81
CDIPT
CHODL
CLDND2
CREB3
CREB3L1
CYB561
CYB5B
CYP4F2
DEFB103A
DEFB103B
DEFB127
DNAJC30
EBPL
EMC6
EMP1
ERG28
ERGIC3
ESRRG
FA2H
FAM209A
FAXDC2
FCER1G
FETUB
FIS1
FKBP8
FUNDC2
FXYD3
FXYD6
GIMAP1
GIMAP5
GJB2
GJB6
GLP1R
GOSR2
GPR152
HMOX2
HSD17B13
IER3IP1
INSIG2
JAGN1
LDLRAD1
LEMD1
LPCAT2
LRP10
LRRC59
LTC4S
MFSD6
MITF
MMP14
MS4A13
MTNR1B
NAT8
NDUFA3
NDUFB11
NEU1
NINJ1
NINJ2
NKG7
ODF4
ORMDL1
ORMDL2
ORMDL3
OTOP3
PLLP
PLP2
PLPP6
PMP22
PNLIPRP1
PTPN9
PVR
RNF152
RTP2
RUSF1
SACM1L
SCAMP4
SEC22B
SERP1
SERP2
SFXN5
SLC35G1
SLC3A2
SLC41A2
SMAGP
SMCO4
SMIM1
SMIM3
SNORC
STX12
STX1B
STX5
STX6
STX7
STX8
SYNGR1
SYNJ2BP
SYS1
TBC1D20
THBD
TIMM23
TLCD1
TLCD4
TMBIM6
TMEM100
TMEM11
TMEM120B
TMEM140
TMEM147
TMEM14B
TMEM14C
TMEM167B
TMEM199
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM239
TMEM242
TMEM243
TMEM254
TMEM31
TMEM42
TMEM51
TMEM60
TMEM65
TMEM86A
TMEM86B
TMEM97
TMIE
TRARG1
TREX1
TSNARE1
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93B1
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAPA
VAPB
YIF1A
YIPF1
YIPF4
YIPF6
ZDHHC24
ZFPL1
Entrez ID
2207
10682
HPRD ID
00916
02192
Ensembl ID
ENSG00000158869
ENSG00000147155
Uniprot IDs
P30273
A0A024QYX0
Q15125
PDB IDs
6OHT
6OHU
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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