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SPNS3 and PLP1
Data Source:
BioGRID
(two hybrid)
SPNS3
PLP1
Description
sphingolipid transporter 3 (putative)
proteolipid protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Plasma Membrane
Integrin Alphav-beta3 Complex
Myelin Sheath
Synapse
Molecular Function
Transmembrane Transporter Activity
Structural Molecule Activity
Protein Binding
Structural Constituent Of Myelin Sheath
Biological Process
Lipid Transport
Transmembrane Transport
Inflammatory Response
Chemical Synaptic Transmission
Axon Ensheathment
Positive Regulation Of Gene Expression
Astrocyte Development
Substantia Nigra Development
Central Nervous System Myelination
Positive Regulation Of Cell Migration
Neuron Projection Development
Long-chain Fatty Acid Biosynthetic Process
Axon Development
AMPA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Coronary artery disease in type 1 diabetes (
29695241
)
Obesity-related traits (
23251661
)
Small cell lung carcinoma (
28604730
)
Interacting Genes
8 interacting genes:
BTN2A2
FXYD3
LRRC25
PLP1
STATH
STRIT1
SYNGR1
TMEM60
86 interacting genes:
ADGRG3
AKT1
AQP10
AQP6
ARL13B
BCL2L13
BIK
CALN1
CALR
CANX
CD40
CD74
CDIPT
CLDN2
CLDN20
CLEC2D
CLN8
CREB3
CREB3L1
CYBC1
DCT
DYSF
EDA2R
ELOVL4
ERGIC3
FAM209A
FCRL2
FFAR2
FNDC9
GAST
GPR42
GPR61
HAS3
HTR2C
IER3IP1
IFITM3
ITGAV
JAGN1
JPH1
KLRC1
LEPROTL1
LEUTX
LHFPL5
LMNA
MAG
MBP
MFF
MGST3
MS4A3
MS4A4A
MTIF3
MUC1
MYADM
NRG1
PI16
PIGP
PTPRN
RELL2
RMDN3
RNF24
SLC10A6
SLC16A2
SLC18A1
SLC1A5
SLC26A6
SLC35E2A
SLC35E3
SLC41A3
SMIM3
SPNS3
STX1A
STX4
SUSD3
TMEM106C
TMEM14B
TMEM182
TMEM242
TMEM243
TMEM254
TMEM31
TMEM45B
TMEM52B
TMEM97
TMPRSS2
UPK2
VAT1
Entrez ID
201305
5354
HPRD ID
14531
02321
Ensembl ID
ENSG00000182557
ENSG00000123560
Uniprot IDs
Q6ZMD2
A0A0S2Z4D4
A8K9L3
B4DI30
P60201
PDB IDs
2XPG
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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