PLP1 and CDIPT

Data Source:
BioGRID (two hybrid)

		PLP1	CDIPT
Description		proteolipid protein 1	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integrin Alphav-beta3 Complex Myelin Sheath Synapse	Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding
	Biological Process	Inflammatory Response Chemical Synaptic Transmission Axon Ensheathment Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Positive Regulation Of Cell Migration Neuron Projection Development Long-chain Fatty Acid Biosynthetic Process Axon Development AMPA Selective Glutamate Receptor Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transport	Phosphatidylinositol Biosynthetic Process
Pathways			Synthesis of PI
Drugs			scyllo-inositol
Diseases		Hereditary spastic paraplegia (SPG) Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS			Mean platelet volume ( 27863252)
Interacting Genes		86 interacting genes: ADGRG3 AKT1 AQP10 AQP6 ARL13B BCL2L13 BIK CALN1 CALR CANX CD40 CD74 CDIPT CLDN2 CLDN20 CLEC2D CLN8 CREB3 CREB3L1 CYBC1 DCT DYSF EDA2R ELOVL4 ERGIC3 FAM209A FCRL2 FFAR2 FNDC9 GAST GPR42 GPR61 HAS3 HTR2C IER3IP1 IFITM3 ITGAV JAGN1 JPH1 KLRC1 LEPROTL1 LEUTX LHFPL5 LMNA MAG MBP MFF MGST3 MS4A3 MS4A4A MTIF3 MUC1 MYADM NRG1 PI16 PIGP PTPRN RELL2 RMDN3 RNF24 SLC10A6 SLC16A2 SLC18A1 SLC1A5 SLC26A6 SLC35E2A SLC35E3 SLC41A3 SMIM3 SPNS3 STX1A STX4 SUSD3 TMEM106C TMEM14B TMEM182 TMEM242 TMEM243 TMEM254 TMEM31 TMEM45B TMEM52B TMEM97 TMPRSS2 UPK2 VAT1	56 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SDCBP SIGLEC12 SLC10A6 SLC16A7 SLC7A1 TLCD4 TMX2 UNC93A VMA21
Entrez ID		5354	10423
HPRD ID		02321	12063
Ensembl ID		ENSG00000123560	ENSG00000103502
Uniprot IDs		A0A0S2Z4D4 A8K9L3 B4DI30 P60201	A8K3L7 B3KY94 O14735
PDB IDs		2XPG
Enriched GO Terms of Interacting Partners?
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