ELF5 and FRZB

Data Source:
BioGRID (two hybrid)

		ELF5	FRZB
Description		E74 like ETS transcription factor 5	frizzled related protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Space Cytoplasm Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Wnt-protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation	Skeletal System Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549 28869591) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)
Interacting Genes		9 interacting genes: ACTR2 FRZB GLRX2 NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		2001	2487
HPRD ID		05525	07282
Ensembl ID		ENSG00000135374	ENSG00000162998
Uniprot IDs		A0A087X1W9 A8K443 Q9UKW6	D9ZGF6 Q92765
PDB IDs		1WWX
Enriched GO Terms of Interacting Partners?
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