FRZB and EHF

Data Source:
BioGRID (two hybrid)

		FRZB	EHF
Description		frizzled related protein	ETS homologous factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane	Chromatin Nucleus Nucleoplasm Golgi Apparatus
	Molecular Function	Protein Binding Wnt-protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity
	Biological Process	Skeletal System Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Multicellular Organism Development Cell Differentiation Epithelial Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549 28869591) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)	Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Prostate-specific antigen levels ( 28139693) Response to antipsychotic treatment ( 21107309) Systemic lupus erythematosus ( 24871463) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Volumetric brain MRI ( 17903297)
Interacting Genes		8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1	2 interacting genes: APP FRZB
Entrez ID		2487	26298
HPRD ID		07282	16105
Ensembl ID		ENSG00000162998	ENSG00000135373
Uniprot IDs		D9ZGF6 Q92765	Q9NZC4
PDB IDs
Enriched GO Terms of Interacting Partners?
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