FRZB and PNO1

Data Source:
BioGRID (two hybrid)

		FRZB	PNO1
Description		frizzled related protein	partner of NOB1 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Membrane	Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding Wnt-protein Binding	RNA Binding Protein Binding
	Biological Process	Skeletal System Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549 28869591) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)
Interacting Genes		8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1	11 interacting genes: ATP5F1C FRZB GSTP1 IGFBP5 KLF6 NOB1 PDPK1 PICK1 RXRG SGSM2 SUPT5H
Entrez ID		2487	56902
HPRD ID		07282	14250
Ensembl ID		ENSG00000162998	ENSG00000115946
Uniprot IDs		D9ZGF6 Q92765	Q9NRX1
PDB IDs			6G18 6G4S 6G4W 6G51 6G53 6G5I
Enriched GO Terms of Interacting Partners?
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