ELF5 and RPS15A

Data Source:
HPRD (two hybrid)

		ELF5	RPS15A
Description		E74 like ETS transcription factor 5	ribosomal protein S15a
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GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm Cytosol Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Population Proliferation Response To Virus Viral Transcription Positive Regulation Of Cell Cycle
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)	Blood protein levels ( 29875488) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: ACTR2 FRZB GLRX2 NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	12 interacting genes: CALM1 CDC37 DDX39B DUX4 ELF5 ERCC6 EWSR1 FBXO7 PTEN RHOU UBE3A VHL
Entrez ID		2001	6210
HPRD ID		05525	04723
Ensembl ID		ENSG00000135374	ENSG00000134419
Uniprot IDs		A0A087X1W9 A8K443 Q9UKW6	B2R4W8 P62244
PDB IDs		1WWX	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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