DTX3 and ARF5

		DTX3	ARF5
Description		deltex E3 ubiquitin ligase 3	ADP ribosylation factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Type 2 diabetes ( 23532257)
Interacting Genes		44 interacting genes: ARF5 BAG3 DTX1 DTX2 EPM2AIP1 FAM90A1 FYN GRB2 MAPK9 NCK2 NFKBID NOTCH2 OSTF1 PARP11 PTK6 RNF141 RNF38 TCEANC TRAF4 TRIP10 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP YES1 ZDHHC17 ZMYND19	14 interacting genes: ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DTX3 ERBB2 GGA1 GORAB IKBKG PIP5K1A RAB11A RAB11FIP3
Entrez ID		196403	381
HPRD ID		16842	00055
Ensembl ID		ENSG00000178498	ENSG00000004059
Uniprot IDs		A0A024RB96 Q8N9I9	A4D0Z3 P84085
PDB IDs			2B6H
Enriched GO Terms of Interacting Partners?
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