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DTX3 and UBE2H
Data Source:
BioGRID
(two hybrid)
DTX3
UBE2H
Description
deltex E3 ubiquitin ligase 3
ubiquitin conjugating enzyme E2 H
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nucleus
Cytosol
Molecular Function
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Notch Signaling Pathway
Protein Ubiquitination
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31152163
31451708
)
Lymphocyte counts (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Response to antidepressants and depression (
27622933
)
White blood cell count (
32888494
)
Interacting Genes
44 interacting genes:
ARF5
BAG3
DTX1
DTX2
EPM2AIP1
FAM90A1
FYN
GRB2
MAPK9
NCK2
NFKBID
NOTCH2
OSTF1
PARP11
PTK6
RNF141
RNF38
TCEANC
TRAF4
TRIP10
UBASH3A
UBASH3B
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2DNL
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2K
UBE2L3
UBE2L6
UBE2V1
UBE2W
UEVLD
USP1
USP2
USP21
XIAP
YES1
ZDHHC17
ZMYND19
68 interacting genes:
BRAP
BYSL
CBLC
CD99
CDK2
DTX3
DTX3L
DZIP3
EPS15
GOLGA2
H2AC18
HBP1
HDAC6
JADE1
LNX2
LRSAM1
MAEA
MARCHF1
MARCHF10
MARCHF2
MARCHF4
MARCHF8
MKRN3
NEURL1
NHLRC1
POLL
POLM
PRKN
PSME3
RAG1
RELA
RNF10
RNF103
RNF113B
RNF114
RNF128
RNF133
RNF139
RNF144A
RNF146
RNF166
RNF185
RNF186
RNF2
RNF34
RNF38
RNF4
RNF6
STAM2
TLE5
TRAIP
TRIM17
TRIM2
TRIM21
TRIM23
TRIM27
TRIM28
TRIM36
TRIM37
TRIM5
TRIM56
TRIM69
TRIM72
UBA1
UBASH3B
UBOX5
UBR2
UBR3
Entrez ID
196403
7328
HPRD ID
16842
03052
Ensembl ID
ENSG00000178498
ENSG00000186591
Uniprot IDs
A0A024RB96
Q8N9I9
A0A3B3IU20
A4D1L5
P62256
PDB IDs
2Z5D
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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