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MIR200B and SF3B1
Data Source:
BioGRID
(unspecified method)
MIR200B
SF3B1
Description
microRNA 200b
splicing factor 3b subunit 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U2 SnRNP
U12-type Spliceosomal Complex
Nuclear Speck
U11/U12 SnRNP
U2-type Prespliceosome
U2-type Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
MRNA Binding
Protein Binding
Splicing Factor Binding
Biological Process
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Negative Regulation Of Myotube Differentiation
Negative Regulation Of Angiogenesis
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Vascular Wound Healing
Positive Regulation Of Cell Cycle Arrest
Negative Regulation Of Interleukin-33 Production
Negative Regulation Of Cardiac Muscle Cell Differentiation
Spliceosomal Complex Assembly
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Splicing
Positive Regulation Of Gene Expression, Epigenetic
Pathways
B-WICH complex positively regulates rRNA expression
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Drugs
H3B-8800
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Major depressive disorder (
27479909
)
Morning person (
30696823
)
Schizophrenia (
25056061
29483656
30285260
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
83 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
CDC5L
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI2
NOL6
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PTCD3
PUF60
PUM1
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SART3
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
100 interacting genes:
APBB1
C11orf58
CALM1
CLK1
CSNK2A1
DUX4
DYRK1A
ERG
IL7R
MELK
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYC
NUDT21
PHF5A
PLRG1
PPP1R8
PRPF40A
SF1
SF3B3
SF3B6
SMAD1
SMAD5
SMAD9
SNIP1
SUMO2
TCERG1
TOP1
U2AF2
WBP4
Entrez ID
406984
23451
HPRD ID
09281
Ensembl ID
ENSG00000207730
ENSG00000115524
Uniprot IDs
B4DGZ4
O75533
PDB IDs
2F9D
2F9J
2FHO
2PEH
3LQV
4OZ1
5IFE
5O9Z
5Z56
5Z57
5Z58
5ZYA
6AH0
6EN4
6FF4
6FF7
6N3E
6QX9
6Y50
6Y53
6Y5Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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