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DVL3 and CEP76
Data Source:
BioGRID
(two hybrid)
DVL3
CEP76
Description
dishevelled segment polarity protein 3
centrosomal protein 76
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Cytosol
Centrosome
Centriole
Cytosol
Protein-containing Complex
Molecular Function
Protease Binding
Signaling Receptor Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Small GTPase Binding
Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Response To Drug
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Centriole Replication
Ciliary Basal Body-plasma Membrane Docking
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Major depressive disorder (
22472876
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Interacting Genes
164 interacting genes:
ABT1
ADAP1
AKAP17A
ANKRD36B
AP3M1
AXIN1
BAHD1
BEND7
BHLHE40
C1orf35
C8orf33
CBX8
CCDC33
CCNK
CCNL1
CDYL2
CEP57L1
CEP70
CEP76
CLK1
CSNK1D
CSNK1E
CSNK2A1
CT45A10
CT45A3
CTNNB1
CYSRT1
DAB2
DDX54
DIDO1
DPPA2
DVL1
EIF1B
EIF3D
ENKD1
FAM13C
FAM90A1
FARS2
FGF16
FLACC1
GADD45GIP1
HOMER3
HOXA5
HOXC5
HOXC8
INO80B
KAT7
KAZN
KCTD10
KCTD7
KLF1
KLF15
KLF3
KLF4
KLHL12
LENG8
LNX1
LONRF1
LRRK2
LUZP4
LY6H
MAB21L3
MAGEB4
MAGOHB
MARK2
MATN2
NFYA
NKD1
NOL12
NXF1
PATZ1
PHF19
PIK3CB
PITX1
PLAGL2
PLN
PNKP
PPM1A
PPP1R16B
PPP2CA
PRKAA2
PRPF18
PRPF3
PRPF31
PRPF38A
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSME3
PSMF1
RBM15B
RBM39
RNF151
RPL11
RPS10
RRP8
RWDD2B
SAP30L
SHFL
SNIP1
SNX22
SORBS3
STOM
SUV39H1
SYT6
SYTL4
TBPL1
TCEA2
TCEANC
TFG
THAP7
TLE5
TNFAIP8L1
TNP1
TPTEP2-CSNK1E
TRAF2
TRIM41
TRIM54
TSN
TSPYL1
TSPYL6
UTP3
VANGL1
VAX1
WDR25
WT1
XPA
YTHDC1
ZBTB24
ZBTB26
ZBTB47
ZBTB48
ZBTB8A
ZFP57
ZNF165
ZNF2
ZNF264
ZNF319
ZNF408
ZNF417
ZNF441
ZNF444
ZNF497
ZNF512B
ZNF552
ZNF581
ZNF648
ZNF696
ZNF697
ZNF699
ZNF71
ZNF764
ZNF774
ZNF775
ZNF792
ZNF821
ZNF837
ZRSR2
ZSCAN21
ZSCAN22
ZSCAN25
105 interacting genes:
AKAP7
AKT1
ANKRD36
ASH2L
BANP
C22orf39
CABP5
CACNB3
CAPN3
CAVIN3
CCDC92
CCNK
CDK18
CENPI
CIR1
COIL
CRYBA4
CSNK1G1
CUTC
CWF19L2
DCTD
DDX6
DEAF1
DMTN
DVL3
DZIP1L
EAF1
EIF1AD
EP400P1
ERCC3
FAM90A1
GDAP2
GFAP
GORASP2
HSF2
HSPB7
ILVBL
IQUB
KDM1A
KDM4D
KIAA1143
KIFBP
KLHDC4
L3MBTL2
LATS1
LNX1
MAGEA11
MBD3
MFAP1
MISP
MLH1
MYOZ1
NEK6
NFYC
NHLRC2
NME5
PAICS
PARD6B
PATZ1
PDGFRB
PDRG1
PDZD4
PDZD7
PIN1
PKP1
PLA2G6
PLCB1
POM121
RADIL
RALGPS1
RBM41
RIPPLY3
RNF128
RPL9
SALL2
SCNM1
SH2D4A
SINHCAF
SMG9
SPG21
STK26
SUOX
TBC1D27P
TCEA2
TCEANC
TCF19
TFAP2D
THRA
TOB2
TSPOAP1
TSSC4
TTC21A
TTLL10
TUFT1
TXNDC9
VEZF1
WDFY3
YY1
ZBTB24
ZBTB4
ZMAT2
ZNF185
ZNF653
ZNF76
ZNF85
Entrez ID
1857
79959
HPRD ID
03222
12694
Ensembl ID
ENSG00000161202
ENSG00000101624
Uniprot IDs
Q92997
Q9UG07
B4DP81
Q8TAP6
PDB IDs
6V7O
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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