DEFA6 and SGTB

Data Source:
BioGRID (two hybrid)

		DEFA6	SGTB
Description		defensin alpha 6	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen	Membrane TRC Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Molecular Adaptor Activity
	Biological Process	Innate Immune Response In Mucosa Antimicrobial Humoral Response Antibacterial Humoral Response Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Fungus Membrane Disruption In Other Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding
Pathways		Defensins Alpha-defensins
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Dental caries (decayed and filled deciduous teeth) ( 31533690) Night sleep phenotypes ( 27126917)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: APP SGTB UBQLN1 UBQLN2	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		1671	54557
HPRD ID		02719	18049
Ensembl ID		ENSG00000164822	ENSG00000197860
Uniprot IDs		Q01524	Q96EQ0
PDB IDs		1ZMQ 3QTE
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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