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TLE5 and KRTAP6-2
Data Source:
BioGRID
(two hybrid)
TLE5
KRTAP6-2
Description
TLE family member 5, transcriptional modulator
keratin associated protein 6-2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Transcription Regulator Complex
Cytosol
Intermediate Filament
Molecular Function
Transcription Corepressor Activity
Protein Binding
Repressing Transcription Factor Binding
Protein Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
Multicellular Organism Development
Animal Organ Morphogenesis
Negative Regulation Of Gene Expression
Wnt Signaling Pathway
Cellular Response To Extracellular Stimulus
Negative Regulation Of Protein Binding
Regulation Of Growth
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Response To Cytokine Stimulus
Response To Interleukin-1
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Anoikis
Keratinization
Pathways
Repression of WNT target genes
Keratinization
Drugs
Diseases
GWAS
Interacting Genes
362 interacting genes:
ABI2
AEN
AGR2
AKAP8L
ANAPC11
ANKRD11
AR
ARHGAP32
ASB3
ATN1
ATP6V0D1
BAG4
BAHD1
BCL6
BHLHE40
BIRC7
BPIFA1
BYSL
C10orf55
C11orf1
C14orf119
C19orf54
C1orf109
C1orf216
C1orf94
C2CD6
C7orf57
CABP2
CABP4
CABP5
CALCOCO2
CAPN1
CARD9
CCDC120
CCDC57
CCL7
CCNJL
CCNK
CCNO
CFAP206
CIB3
CLIC3
CLIP3
CNFN
COA7
CPSF7
CRACR2A
CRX
CSNK2A1
CSTF2
CSTF2T
CT55
CTBP2
CYSRT1
DAZAP2
DCUN1D1
DDX6
DGCR6
DIP2A
DMRT2
DMRT3
DMRTB1
DNMT3L
DOK6
DVL2
DVL3
DYDC1
EAF1
EAF2
EFEMP2
EFHC1
EIF1AD
EIF4E2
ERF
EXOSC5
EYA2
FAM124A
FAM124B
FAM168B
FAM214B
FAM217B
FAM90A1
FANCG
FBF1
FCHSD2
FHL3
FOSB
FOXD2
FOXN1
FOXP2
FRS3
FSD2
GABARAP
GATA1
GCC1
GEM
GFAP
GFI1B
GIGYF1
GLIS2
GLRX3
GOLGA2
GOLGA6L9
GORASP2
GPANK1
GPATCH2L
GRAP2
GRB2
GRN
GTF2E1
GYS1
HDAC4
HDHD3
HELT
HEXIM2
HGS
HHEX
HMGB1
HNF1A
HNRNPF
HNRNPH2
HNRNPK
HNRNPLL
HOMEZ
HOXA1
HOXB5
HOXC8
HOXC9
IKZF3
INO80B
INO80E
INPP5J
IRX2
IRX6
KANK2
KDM1A
KIFC3
KLF1
KLF4
KLHDC7B
KRT13
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP10-11
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-2
KRTAP13-2
KRTAP13-3
KRTAP17-1
KRTAP19-5
KRTAP19-7
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
L3MBTL2
LDLR
LDOC1
LENG8
LHX3
LINC00526
LMO1
LMO2
LMO4
LSM2
LZTS2
MAGOHB
MAPK1
MAPK14
MAPRE3
MBNL1
MCRS1
MDFI
MED12L
MED25
MED31
MED4
MEIS3
MFAP1
MIA2
MIIP
MKRN3
MLH1
MLLT6
MLX
MORF4L1
MORF4L2
MSS51
MSX1
MSX2
MTUS2
MVP
MYF5
MYH7B
MYO15B
MYOG
NAB2
NAF1
NBPF19
NCDN
NDOR1
NDUFB7
NEK6
NOTCH2NLA
NTAQ1
NUDT22
NUTF2
NUTM1
OLIG3
OSGIN1
OXER1
P4HA3
PARVG
PATZ1
PAX8
PAX9
PCBP1
PCSK5
PFDN5
PHF1
PICK1
PITX1
PITX2
PLAGL1
POLR1C
POU2F1
PPP1R16A
PPP1R16B
PRDM1
PRDM14
PRDM6
PRKAA1
PRKAA2
PRKAB2
PROP1
PRPF31
PRR3
PRR35
PSMB1
PSMB4
PSMF1
PTRH2
QARS1
RAD51D
RBM10
RBPMS
REL
RELA
RFX6
RHOXF2
RIBC1
RIMBP3
RIPPLY1
RNF31
RORB
RPL18A
RUNX1
RUSC1
SAT1
SCNM1
SDCBP
SERTAD3
SET
SF3B4
SH2B2
SH3GL3
SHFL
SHISA6
SIX1
SIX2
SIX3
SIX6
SKIL
SMAD3
SMAD4
SMARCB1
SMARCD1
SNCAIP
SNRPA
SNRPC
SOHLH1
SOX5
SPATA25
SPG21
SRPK2
SSC4D
STK16
STX11
SUFU
SUPT5H
TBX3
TBX6
TCEANC
TCF4
TCF7L2
TEAD4
TENT5B
TEX37
TFAP2D
THAP7
TIGD3
TMCC2
TNS2
TOX3
TRAF1
TRAF2
TRIB3
TRIM26
TRIM27
TRIM41
TRIP6
TRMT2A
TSC1
TSC22D4
TSEN15
TSGA10
TSGA10IP
TSSK3
TTC23
U2AF2
UBAP2
UBE2H
UBL5
UBXN11
USP2
USP54
VEZF1
VGLL1
VIM
VPS37B
VPS37C
YPEL3
YTHDF1
ZBTB16
ZBTB24
ZBTB47
ZFHX3
ZGPAT
ZIC1
ZMYND12
ZNF330
ZNF34
ZNF383
ZNF408
ZNF414
ZNF417
ZNF467
ZNF48
ZNF503
ZNF524
ZNF576
ZNF688
ZNF792
ZNF835
ZRANB1
185 interacting genes:
ADAM12
ADAMTSL4
ANAPC11
ANKS1A
ANXA11
APOBEC1
AQP1
ARID5A
ATG9A
ATN1
ATPAF2
BEX2
BHLHE40
C10orf55
C1orf94
C20orf85
C6orf15
CAMK2A
CAMK2B
CASC3
CATSPER1
CCDC120
CCDC17
CCDC28A-AS1
CCER1
CCNK
CELF5
CERCAM
CERK
CFP
CHIC2
COL8A1
CREB5
CTRC
CYSRT1
DAZAP2
DHRS1
DMRT3
ENKD1
ESR2
FAAP20
FAM166B
FAM168A
FAM214B
FAM83A
FOXD2
FOXD4L1
FOXD4L3
FOXP3
FRS3
GALT
GATA3
GCM2
GLIS2
GLYCTK
GNE
GPS2
GRINA
GRN
GSTP1
HAPLN2
HELT
HEY1
HEY2
HEYL
HHEX
HOXA1
HOXB9
HOXC8
HOXC9
HSF4
HYAL2
IGFN1
INCA1
INO80B
ITGB4
KLHL38
KPRP
KRT83
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP15-1
KRTAP19-5
KRTAP26-1
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP6-1
KRTAP6-3
LASP1
LCE2B
LCE2D
LCE5A
LETM1
LGALS9C
LRFN4
LRRC41
LYVE1
MEIS2
MGAT5B
MKRN3
NAF1
NDUFA9
NEU4
NFKBID
NID2
NPBWR2
NR1D2
NSD1
OLIG3
OTX1
PATL1
PATZ1
PAX3
PDP1
PHLDA1
PITX1
PKD2
PLEKHN1
PLSCR4
POGZ
POU5F2
PPP1R32
PRR13
PRR3
PRR30
PRR35
RASD1
RBFOX2
RBPMS2
RERE
RHOXF2
RNF38
ROR2
RTP5
RUNX1T1
RUSC1
SAMD7
SHARPIN
SIAH3
SMAP2
SMARCC1
SMN1
SMN2
SMUG1
SNRPB
SNRPC
SPAG8
SPATA8
TBX6
TCF7L2
TEKT3
TEKT4
TEKT5
TENT5B
TENT5D
TEPSIN
TEX37
TFAP2D
TLE5
TLX2
TLX3
TNIP1
TOLLIP
TPRX1
TRIP13
TSGA10IP
TSPAN4
TSPYL6
VAC14
VENTX
VGLL3
VPS37C
YPEL3
ZBTB32
ZC3H10
ZIC1
ZNF414
ZNF503
ZNF581
ZNF683
ZNF843
Entrez ID
166
337967
HPRD ID
02556
11219
Ensembl ID
ENSG00000104964
ENSG00000186930
Uniprot IDs
Q08117
Q8WY48
Q3LI66
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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