SEPTIN2 and COG4

Data Source:
BioGRID (two hybrid)

		SEPTIN2	COG4
Description		septin 2	component of oligomeric golgi complex 4
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GO Annotations	Cellular Component	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization
Pathways		Anchoring of the basal body to the plasma membrane	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		21 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 CSNK2A1 DAZAP2 ESR1 JPT2 MTOR PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5	15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9
Entrez ID		4735	25839
HPRD ID		03297	08444
Ensembl ID		ENSG00000168385	ENSG00000103051
Uniprot IDs		A0A384N6H6 Q15019	A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3
PDB IDs		2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR	3HR0
Enriched GO Terms of Interacting Partners?
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