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SMYD1 and WDR77
Data Source:
BioGRID
(two hybrid)
SMYD1
WDR77
Description
SET and MYND domain containing 1
WD repeat domain 77
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Methylosome
Pole Plasm
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Histone-lysine N-methyltransferase Activity
Metal Ion Binding
Protein Binding
Methyl-CpG Binding
Nuclear Receptor Coactivator Activity
Biological Process
Chromatin Remodeling
Heart Development
Positive Regulation Of Myotube Differentiation
Histone Lysine Methylation
Skeletal Muscle Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Spliceosomal SnRNP Assembly
Regulation Of Transcription By RNA Polymerase II
Pole Plasm Assembly
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription, DNA-templated
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways
snRNP Assembly
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Night sleep phenotypes (
27126917
)
Retinal detachment or retinal break (
31816047
)
Interacting Genes
44 interacting genes:
ARID5A
BACH2
BHLHE40
C11orf1
C11orf16
C11orf53
CCDC113
CCDC33
DISC1
DVL1
FAM166A
FAM204A
FAM83A
FAM86C1P
H3-5
HDAC2
HDAC3
HDHD3
HMG20A
HOMEZ
KIF16B
KRT35
LENG8
MDFI
MEOX2
MYH7B
NACA
NEFL
OGDHL
PATZ1
POU6F2
PRR22
RBM4B
RSPH6A
RUSC1
SNX11
SPAG8
TBRG1
TTC33
USP54
UTP14A
WDR77
ZBTB3
ZBTB44
44 interacting genes:
AQR
BAG2
CDK19
CDK8
CLNS1A
CREBBP
CTDP1
GLI1
GPKOW
H2AC21
HNRNPM
LSM3
NKX3-1
PCBP2
PPIL1
PPP1R8
PQBP1
PRKG1
PRKG2
PRMT5
QKI
RBM5
RIOK1
SAP30BP
SF1
SF3A1
SF3B4
SIRT7
SMAD1
SMYD1
SNRPB
SNRPC
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SUZ12
THOC1
TOE1
YWHAB
YWHAQ
ZMYND19
ZNF207
Entrez ID
150572
79084
HPRD ID
06025
14387
Ensembl ID
ENSG00000115593
ENSG00000116455
Uniprot IDs
E9PHG3
Q5HYE8
Q8NB12
A0A024R0H7
Q9BQA1
PDB IDs
4GQB
4X60
4X61
4X63
5C9Z
5EMJ
5EMK
5EML
5EMM
5FA5
6CKC
6K1S
6RLL
6RLQ
6UXX
6UXY
6V0N
6V0O
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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