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SMYD1 and BHLHE40
Data Source:
BioGRID
(two hybrid)
SMYD1
BHLHE40
Description
SET and MYND domain containing 1
basic helix-loop-helix family member e40
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Chromatin
Nucleus
Cytoplasm
Nuclear Body
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Histone-lysine N-methyltransferase Activity
Metal Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
MRF Binding
Protein Heterodimerization Activity
E-box Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Chromatin Remodeling
Heart Development
Positive Regulation Of Myotube Differentiation
Histone Lysine Methylation
Skeletal Muscle Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Circadian Rhythm
Anterior/posterior Pattern Specification
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Regulation Of Neurogenesis
Pathways
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Night sleep phenotypes (
27126917
)
Retinal detachment or retinal break (
31816047
)
Medication use (thyroid preparations) (
31015401
)
Multiple sclerosis (
31604244
)
Psoriasis vulgaris (
26626624
)
Thrombin-activatable fibrinolysis inhibitor activation peptide (
29378355
)
Interacting Genes
44 interacting genes:
ARID5A
BACH2
BHLHE40
C11orf1
C11orf16
C11orf53
CCDC113
CCDC33
DISC1
DVL1
FAM166A
FAM204A
FAM83A
FAM86C1P
H3-5
HDAC2
HDAC3
HDHD3
HMG20A
HOMEZ
KIF16B
KRT35
LENG8
MDFI
MEOX2
MYH7B
NACA
NEFL
OGDHL
PATZ1
POU6F2
PRR22
RBM4B
RSPH6A
RUSC1
SNX11
SPAG8
TBRG1
TTC33
USP54
UTP14A
WDR77
ZBTB3
ZBTB44
89 interacting genes:
AAMP
AANAT
APH1A
ARNTL
ATXN1
BHLHE41
BRD7
BYSL
CALML3
CCNK
CDPF1
CHD3
COX5B
CREM
DAB1
DAZAP2
DVL3
EHHADH
ENO1
FAM83A
FBLN1
GMCL2
GPSM1
HDAC1
HIVEP1
HNRNPLL
KLHDC7B
KRTAP1-3
KRTAP19-1
KRTAP19-5
KRTAP19-7
KRTAP23-1
KRTAP6-1
KRTAP6-2
KRTAP8-1
LARP4
LASP1
LMO3
MAGED1
MCRS1
MYOD1
NAA50
NEK6
NOC4L
NUMBL
PDE6G
PFDN5
PHF1
PLEKHB2
POU6F2
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAD54L2
RBFOX1
RBM23
RBPMS
RBPMS2
RHOBTB3
RHOJ
ROR2
SETDB1
SIN3A
SMAP2
SMARCB1
SMYD1
SOGA1
SOX15
STAT3
STK19
TCF3
TENT5A
TENT5B
TLE5
TOB2
TOLLIP
TTC23
TXNL4B
UBE2I
USP54
VAC14
VENTX
VIM
WT1
ZFHX3
ZHX1
Entrez ID
150572
8553
HPRD ID
06025
16050
Ensembl ID
ENSG00000115593
ENSG00000134107
Uniprot IDs
E9PHG3
Q5HYE8
Q8NB12
O14503
Q6IB83
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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