CYB5R3 and VMP1

Data Source:
BioGRID (two hybrid)

		CYB5R3	VMP1
Description		cytochrome b5 reductase 3	vacuole membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex	Phagophore Assembly Site Autophagosome Membrane Nucleolus Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding	Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation	Autophagosome Assembly Autophagy Golgi Organization Embryo Implantation Cell Junction Assembly Cell-cell Adhesion
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia
GWAS		Initial pursuit acceleration ( 29064472)	Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hematocrit ( 32888494 27863252) Hemoglobin ( 29403010 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Idiopathic dilated cardiomyopathy ( 29495422) Lymphocyte counts ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 24076602) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 27841878) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15	7 interacting genes: CYB5R3 ERGIC3 FAM209A HGS LMNA MEOX2 SLC39A9
Entrez ID		1727	81671
HPRD ID		08942	15649
Ensembl ID		ENSG00000100243	ENSG00000062716
Uniprot IDs		P00387	B4DED7 B4DEJ9 B4DGZ7 D3DU01 Q96GC9
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?
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