CYB5R3 and NSG1

Data Source:
BioGRID (two hybrid)

		CYB5R3	NSG1
Description		cytochrome b5 reductase 3	neuronal vesicle trafficking associated 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex	Nucleus Cytoplasm Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding
	Biological Process	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Dopamine Receptor Signaling Pathway Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases		Methemoglobinemia
GWAS		Initial pursuit acceleration ( 29064472)
Interacting Genes		61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15	32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2
Entrez ID		1727	27065
HPRD ID		08942	09624
Ensembl ID		ENSG00000100243	ENSG00000168824
Uniprot IDs		P00387	B2R5R8 P42857
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?
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