RNF38 and RNF114

Data Source:
BioGRID (two hybrid)

		RNF38	RNF114
Description		ring finger protein 38	ring finger protein 114
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Sperm Flagellum	Nucleus Cytosol Plasma Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Male Gonad Development Protein Ubiquitination	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172)	Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		25 interacting genes: CYSRT1 DTX3 DZIP3 KPRP KRTAP10-8 KRTAP11-1 KRTAP19-5 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 OXER1 RNF114 RNF208 RUNX1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2N ZDHHC17	29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1
Entrez ID		152006	55905
HPRD ID		11519	10329
Ensembl ID		ENSG00000137075	ENSG00000124226
Uniprot IDs		Q9H0F5	Q9Y508
PDB IDs		1X4J 4V3K 4V3L
Enriched GO Terms of Interacting Partners?
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