RNF114 and AK5

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF114	AK5
Description		ring finger protein 114	adenylate kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Cytoplasm Cytosol Centriolar Satellite
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Multicellular Organism Development Spermatogenesis Cell Differentiation	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion ATP Metabolic Process Nucleoside Monophosphate Phosphorylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)	Body mass index ( 25673413) Chronotype ( 26955885 30696823 27494321) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes (age of onset) ( 28060188) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1	7 interacting genes: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH
Entrez ID		55905	26289
HPRD ID		10329	10472
Ensembl ID		ENSG00000124226	ENSG00000154027
Uniprot IDs		Q9Y508	Q9Y6K8
PDB IDs			2BWJ
Enriched GO Terms of Interacting Partners?
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