RNF114 and TRIM52

Data Source:
BioGRID (two hybrid)

		RNF114	TRIM52
Description		ring finger protein 114	tripartite motif containing 52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Nucleus Cytoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Multicellular Organism Development Spermatogenesis Cell Differentiation	Protein Ubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Protein Autoubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1	5 interacting genes: APP NEDD4 RNF114 RNF126 TRIM41
Entrez ID		55905	84851
HPRD ID		10329	10283
Ensembl ID		ENSG00000124226	ENSG00000183718
Uniprot IDs		Q9Y508	Q96A61
PDB IDs
Enriched GO Terms of Interacting Partners?
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