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COMMD1 and CUL7
Data Source:
BioGRID
(pull down)
COMMD1
CUL7
Description
copper metabolism domain containing 1
cullin 7
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Endosome Membrane
Cul2-RING Ubiquitin Ligase Complex
Recycling Endosome
Anaphase-promoting Complex
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Cullin-RING Ubiquitin Ligase Complex
Cul7-RING Ubiquitin Ligase Complex
Perinuclear Region Of Cytoplasm
3M Complex
Molecular Function
Copper Ion Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Sodium Channel Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylinositol-3,4-bisphosphate Binding
Phosphatidic Acid Binding
Phosphatidylinositol-3,5-bisphosphate Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Nucleotide-excision Repair
Golgi To Plasma Membrane Transport
Protein Transport
Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Modification
Plasma Membrane To Endosome Transport
Copper Ion Homeostasis
Negative Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Protein Localization To Cell Surface
Microtubule Cytoskeleton Organization
Mitotic Cytokinesis
Vasculogenesis
Epithelial To Mesenchymal Transition
Placenta Development
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Golgi Organization
Regulation Of Mitotic Nuclear Division
Viral Process
Protein Ubiquitination
IRE1-mediated Unfolded Protein Response
Post-translational Protein Modification
Positive Regulation Of Dendrite Morphogenesis
Pathways
Neddylation
XBP1(S) activates chaperone genes
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
3M syndrome
GWAS
Age-related nuclear cataracts (
33311586
)
Erectile dysfunction (
30583798
)
Height (
31562340
)
Iron status biomarkers (total iron binding capacity) (
28334935
)
Mean corpuscular volume (
27863252
)
Nonalcoholic fatty liver disease (
31311600
)
Interacting Genes
31 interacting genes:
BAHCC1
BARD1
BRCA1
COMMD10
COMMD2
COMMD3
COMMD4
COMMD5
COMMD6
COMMD7
COMMD8
CUL1
CUL2
CUL3
CUL4A
CUL4B
CUL5
CUL7
ELOC
KAT2A
LIG4
NFKBIA
PRKN
RELA
SLC12A2
SOCS1
SOD1
SPP1
TCEAL8
UPRT
XIAP
9 interacting genes:
COMMD1
FBXW8
MEGF10
MTDH
MTNR1A
PLXNB3
RBX1
SKP1
UBE2M
Entrez ID
150684
9820
HPRD ID
06253
09901
Ensembl ID
ENSG00000173163
ENSG00000044090
Uniprot IDs
Q8N668
Q14999
PDB IDs
2H2M
2JNG
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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