ODF4 and TMBIM6

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ODF4	TMBIM6
Description		outer dense fiber of sperm tails 4	transmembrane BAX inhibitor motif containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Endoribonuclease Inhibitor Activity
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation	Negative Regulation Of Immunoglobulin Production Autophagy Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Protein Binding Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of RNA Splicing Cellular Response To Unfolded Protein Negative Regulation Of Apoptotic Process Negative Regulation Of Endoribonuclease Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Response To L-glutamate Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)	General cognitive ability ( 29844566)
Interacting Genes		23 interacting genes: APP CACNG1 CD9 CDIPT CNIH3 DEFB103A DEFB103B EBP LAPTM4B MARCHF5 MEOX2 MS4A13 NINJ2 RUSF1 SACM1L SLC25A46 SLC38A7 TMBIM6 TMEM119 TMEM239 TOMM6 TRARG1 YIPF6	68 interacting genes: ADIPOR2 ATP13A1 BCL2 BCL2L1 CD300LG CD79A CD99L2 CDC7 CERS2 CLDN22 COBLL1 CREB3L1 EBP ENPP4 ERP29 ESAM FAM209A FERD3L FGFBP2 FXYD3 GJA5 GJA8 GJB4 GLP1R GPHB5 GPR151 GPR42 GPX8 GYPA GZMK HERPUD2 HJV HTR2C IER3 JSRP1 KCNA10 KCNC1 LIME1 LRRC59 MANBAL MFSD14B MMGT1 MS4A3 ODF4 OPRM1 PI16 PIANP PVR REEP2 RHBDL2 RNF185 SCN3B SIT1 SLAMF6 SLC12A7 SLC41A3 SLC7A1 SOAT2 STEAP1B SYT9 TEX29 TMEM31 TMUB1 TMX2 TNFRSF17 TREML1 UGT2B11 VTI1A
Entrez ID		146852	7009
HPRD ID		17658	02851
Ensembl ID		ENSG00000184650	ENSG00000139644
Uniprot IDs		C3TX97 Q2M2E3	A0A024R0Z5 P55061
PDB IDs
Enriched GO Terms of Interacting Partners?
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