CS and CRYAA

Data Source:
HPRD (in vitro)

		CS	CRYAA
Description		citrate synthase	crystallin alpha A
Image
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Binding Citrate (Si)-synthase Activity	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding
	Biological Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Protein Stabilization Response To Stimulus
Pathways		Mitochondrial protein import Citric acid cycle (TCA cycle)
Drugs		Trifluoroacetonyl coenzyme A Coenzyme A Oxaloacetate Ion alpha-Fluoro-carboxymethyldethia coenzyme A complex D-Malic acid Nitromethyldethia coenzyme A Citric acid
Diseases
GWAS		Height ( 31562340 23456168) Inflammatory skin disease ( 25574825) Refractive error ( 32231278)	Age-related nuclear cataracts ( 33311586 24951543) Diastolic blood pressure ( 28135244 27841878 28739976 27618452) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 28739976 27618452)
Interacting Genes		7 interacting genes: CRYAA CRYAB DYNLL1 HSD17B10 HSPB1 LINC01554 MDH2	18 interacting genes: ALB BCL2L1 CRYAA2 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP NTAQ1 SDCBP SPG21
Entrez ID		1431	1409
HPRD ID		00349	00427
Ensembl ID		ENSG00000062485	ENSG00000160202
Uniprot IDs		A0A024RB75 O75390	A0A140G945 P02489
PDB IDs		5UZP 5UZQ 5UZR	6T1R
Enriched GO Terms of Interacting Partners?
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