CRYAA and CS

Data Source:
HPRD (in vitro)

		CRYAA	CS
Description		crystallin alpha A	citrate synthase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Nucleus Mitochondrion Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	RNA Binding Citrate (Si)-synthase Activity
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Protein Stabilization Response To Stimulus	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process
Pathways			Mitochondrial protein import Citric acid cycle (TCA cycle)
Drugs			Trifluoroacetonyl coenzyme A Coenzyme A Oxaloacetate Ion alpha-Fluoro-carboxymethyldethia coenzyme A complex D-Malic acid Nitromethyldethia coenzyme A Citric acid
Diseases
GWAS		Age-related nuclear cataracts ( 33311586 24951543) Diastolic blood pressure ( 28135244 27841878 28739976 27618452) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 28739976 27618452)	Height ( 31562340 23456168) Inflammatory skin disease ( 25574825) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: ALB BCL2L1 CRYAA2 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP NTAQ1 SDCBP SPG21	7 interacting genes: CRYAA CRYAB DYNLL1 HSD17B10 HSPB1 LINC01554 MDH2
Entrez ID		1409	1431
HPRD ID		00427	00349
Ensembl ID		ENSG00000160202	ENSG00000062485
Uniprot IDs		A0A140G945 P02489	A0A024RB75 O75390
PDB IDs		6T1R	5UZP 5UZQ 5UZR
Enriched GO Terms of Interacting Partners?
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