CRYAA and CRYZ

Data Source:
HPRD (in vitro)

		CRYAA	CRYZ
Description		crystallin alpha A	crystallin zeta
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex	Cytosol Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	MRNA 3'-UTR Binding NADPH:quinone Reductase Activity Zinc Ion Binding Identical Protein Binding NADPH Binding NADH Binding
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Protein Stabilization Response To Stimulus	Visual Perception Xenobiotic Catabolic Process Protein Homotetramerization
Pathways
Drugs			Dicoumarol Nicotinamide adenine dinucleotide phosphate Medical Cannabis Nabiximols
Diseases
GWAS		Age-related nuclear cataracts ( 33311586 24951543) Diastolic blood pressure ( 28135244 27841878 28739976 27618452) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 28739976 27618452)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Neurociticism ( 29500382) Resistin levels ( 22843503) Self-reported tiredness ( 28194004)
Interacting Genes		18 interacting genes: ALB BCL2L1 CRYAA2 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP NTAQ1 SDCBP SPG21	1 interacting genes: CRYAA
Entrez ID		1409	1429
HPRD ID		00427	00437
Ensembl ID		ENSG00000160202	ENSG00000116791
Uniprot IDs		A0A140G945 P02489	Q08257
PDB IDs		6T1R	1YB5
Enriched GO Terms of Interacting Partners?
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