UBE2F and UBA3

Data Source:
BioGRID (enzymatic study, enzymatic study)

		UBE2F	UBA3
Description		ubiquitin conjugating enzyme E2 F (putative)	ubiquitin like modifier activating enzyme 3
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GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding ATP Binding NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity	Protein Binding ATP Binding Nuclear Receptor Binding NEDD8 Activating Enzyme Activity NEDD8 Transferase Activity Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation	Cellular Protein Modification Process Proteolysis Endomitotic Cell Cycle Protein Phosphopantetheinylation Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Neddylation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Dectin-1 mediated noncanonical NF-kB signaling NIK-->noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lean body mass ( 28552196)	Meat-related diet ( 32066663)
Interacting Genes		12 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RC3H1 RNF34 RNF7 UBA3	12 interacting genes: CHD3 CPNE2 DUSP23 IMPA2 KDM1A NAE1 NEDD8 TRIM55 TRIM63 UBE2D2 UBE2F UBE2M
Entrez ID		140739	9039
HPRD ID		14812	04413
Ensembl ID		ENSG00000184182	ENSG00000144744
Uniprot IDs		Q969M7	Q8TBC4
PDB IDs		2EDI 3FN1 4GBA	1R4M 1R4N 1TT5 1Y8X 1YOV 2LQ7 2NVU 3DBH 3DBL 3DBR 3FN1 3GZN 5JJM
Enriched GO Terms of Interacting Partners?
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