UBE2F and RNF34

Data Source:
BioGRID (two hybrid)

		UBE2F	RNF34
Description		ubiquitin conjugating enzyme E2 F (putative)	ring finger protein 34
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Endomembrane System Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding ATP Binding NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity	P53 Binding Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Phosphatidylinositol Phosphate Binding
	Biological Process	Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation	Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Protein Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Oxygen Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Regulation of TP53 Degradation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lean body mass ( 28552196)
Interacting Genes		12 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RC3H1 RNF34 RNF7 UBA3	10 interacting genes: APP APPBP2 DNAJA3 MAVS NOD1 PHF7 TRIM23 UBE2D2 UBE2F UBE2H
Entrez ID		140739	80196
HPRD ID		14812	10509
Ensembl ID		ENSG00000184182	ENSG00000170633
Uniprot IDs		Q969M7	A0A087WTM5 Q969K3
PDB IDs		2EDI 3FN1 4GBA
Enriched GO Terms of Interacting Partners?
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