UBA3 and DUSP23

Data Source:
BioGRID (two hybrid)

		UBA3	DUSP23
Description		ubiquitin like modifier activating enzyme 3	dual specificity phosphatase 23
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Binding Nuclear Receptor Binding NEDD8 Activating Enzyme Activity NEDD8 Transferase Activity Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Cellular Protein Modification Process Proteolysis Endomitotic Cell Cycle Protein Phosphopantetheinylation Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Neddylation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle	Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Dectin-1 mediated noncanonical NF-kB signaling NIK-->noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			4-Nitrophenyl Phosphate
Diseases
GWAS		Meat-related diet ( 32066663)	Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		12 interacting genes: CHD3 CPNE2 DUSP23 IMPA2 KDM1A NAE1 NEDD8 TRIM55 TRIM63 UBE2D2 UBE2F UBE2M	32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746
Entrez ID		9039	54935
HPRD ID		04413	07908
Ensembl ID		ENSG00000144744	ENSG00000158716
Uniprot IDs		Q8TBC4	A0A140VJI5 Q9BVJ7
PDB IDs		1R4M 1R4N 1TT5 1Y8X 1YOV 2LQ7 2NVU 3DBH 3DBL 3DBR 3FN1 3GZN 5JJM	2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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