CBLC and OXA1L

Data Source:
BioGRID (two hybrid)

		CBLC	OXA1L
Description		Cbl proto-oncogene C	OXA1L mitochondrial inner membrane protein
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Raft	Mitochondrion Mitochondrial Respirasome Mitochondrial Matrix Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane Integral Component Of Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Phosphotyrosine Residue Binding Epidermal Growth Factor Receptor Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Receptor Tyrosine Kinase Binding Ubiquitin Protein Ligase Activity	Protein Binding Membrane Insertase Activity Protein Homodimerization Activity Mitochondrial Ribosome Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Signal Transduction Cell Surface Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity	Aerobic Respiration Negative Regulation Of ATPase Activity Protein Insertion Into Mitochondrial Inner Membrane From Matrix Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Cytochrome C Oxidase Assembly Protein Insertion Into Membrane Protein Tetramerization Negative Regulation Of Oxidoreductase Activity Protein-containing Complex Assembly Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) LDL cholesterol ( 24507774) Weight ( 28552196)	Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		54 interacting genes: AKT1 BAP1 BIRC2 CCND2 CDK6 CDKN2B CHFR CKM CRK EGFR EPHA2 ERBB2 FGFR4 FYN GLIS2 GRB2 ITCH LATS2 LYN MAP2K3 MDM4 MYC NACAD NF2 NFIC NSD3 OTUD6A OXA1L RAF1 SH3GL3 SHC1 SPRY2 SRC STK11 TERT TGFB1I1 TP53 TRAF4 TRIM46 TRIP6 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2I UBE2K UBE2L3 UBE2L6 UBE2R2 USP2 USP21 YES1 ZAP70	7 interacting genes: CBLC MRPL13 MRPL20 MRPL28 MRPL48 MRPL49 MRPL51
Entrez ID		23624	5018
HPRD ID		09765	03043
Ensembl ID		ENSG00000142273	ENSG00000155463
Uniprot IDs		Q9ULV8	J3KNA0 Q15070 Q2M1J6
PDB IDs		3OP0 3VRN 3VRO 3VRP 3VRQ 3VRR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?