CREBL2 and PKNOX2

Data Source:
BioGRID (two hybrid)

		CREBL2	PKNOX2
Description		cAMP responsive element binding protein like 2	PBX/knotted 1 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Protein Binding Actin Filament Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell Cycle Signal Transduction Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Glucose Import Positive Regulation Of Lipid Biosynthetic Process Protein Stabilization	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systemic lupus erythematosus ( 23273568)	Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)
Interacting Genes		5 interacting genes: CREBRF DDIT3 DNMT3L PKNOX2 UBE2I	32 interacting genes: ARFIP2 C10orf88 C1orf216 CCDC116 CCDC185 CCDC196 CENPP CREBL2 CSTF2T CTTNBP2 CTTNBP2NL DDA1 ENKD1 FAM110B FHL2 HGS HOXB1 IQGAP1 MBD3 MCRS1 MYO15B NRIP1 NUP54 NUP58 PBX4 PICK1 SMARCD1 STK16 TRIB3 TSG101 USHBP1 VPS37C
Entrez ID		1389	63876
HPRD ID		07541	17857
Ensembl ID		ENSG00000111269	ENSG00000165495
Uniprot IDs		O60519	Q96KN3
PDB IDs
Enriched GO Terms of Interacting Partners?
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