PKNOX2 and DDA1

Data Source:
BioGRID (two hybrid)

		PKNOX2	DDA1
Description		PBX/knotted 1 homeobox 2	DET1 and DDB1 associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Protein Binding Actin Filament Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways			Neddylation
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)	Mitochondrial DNA copy number ( 30704525) Systemic lupus erythematosus ( 23273568)
Interacting Genes		32 interacting genes: ARFIP2 C10orf88 C1orf216 CCDC116 CCDC185 CCDC196 CENPP CREBL2 CSTF2T CTTNBP2 CTTNBP2NL DDA1 ENKD1 FAM110B FHL2 HGS HOXB1 IQGAP1 MBD3 MCRS1 MYO15B NRIP1 NUP54 NUP58 PBX4 PICK1 SMARCD1 STK16 TRIB3 TSG101 USHBP1 VPS37C	5 interacting genes: AGTRAP CMTM5 LNX2 PKNOX2 RDH10
Entrez ID		63876	79016
HPRD ID		17857	15107
Ensembl ID		ENSG00000165495	ENSG00000130311
Uniprot IDs		Q96KN3	A0A024R7J7 Q9BW61
PDB IDs			6DSZ 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5
Enriched GO Terms of Interacting Partners?
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