PKNOX2 and MYO15B

Data Source:
BioGRID (two hybrid)

		PKNOX2	MYO15B
Description		PBX/knotted 1 homeobox 2	myosin XVB
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Protein Binding Actin Filament Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)
Interacting Genes		32 interacting genes: ARFIP2 C10orf88 C1orf216 CCDC116 CCDC185 CCDC196 CENPP CREBL2 CSTF2T CTTNBP2 CTTNBP2NL DDA1 ENKD1 FAM110B FHL2 HGS HOXB1 IQGAP1 MBD3 MCRS1 MYO15B NRIP1 NUP54 NUP58 PBX4 PICK1 SMARCD1 STK16 TRIB3 TSG101 USHBP1 VPS37C	95 interacting genes: ABI2 ADAMTSL4 BEND7 BHLHB9 C11orf1 C7orf57 CARD9 CCNC CEP57L1 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PPP1R32 PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2
Entrez ID		63876	80022
HPRD ID		17857
Ensembl ID		ENSG00000165495	ENSG00000266714
Uniprot IDs		Q96KN3	Q96JP2 Q9H614
PDB IDs			2DLP
Enriched GO Terms of Interacting Partners?
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