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H3C14 and BRD1
Data Source:
BioGRID
(unspecified method)
H3C14
BRD1
Description
H3 clustered histone 14
bromodomain containing 1
Image
GO Annotations
Cellular Component
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Extracellular Exosome
Nucleus
Chromosome
Nuclear Speck
Dendrite
Histone H3-K14 Acetyltransferase Complex
Perikaryon
MOZ/MORF Histone Acetyltransferase Complex
Molecular Function
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Protein Binding
Histone Binding
Histone Acetyltransferase Activity (H3-K23 Specific)
Metal Ion Binding
Biological Process
RDNA Heterochromatin Assembly
Chromatin Organization
Nucleosome Assembly
Blood Coagulation
Interleukin-7-mediated Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing By MiRNA
Response To Immobilization Stress
Erythrocyte Maturation
Histone H3 Acetylation
Histone H3-K23 Acetylation
Histone H3-K14 Acetylation
Positive Regulation Of Erythrocyte Differentiation
Response To Electrical Stimulus
Pathways
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Amyloid fiber formation
Factors involved in megakaryocyte development and platelet production
HATs acetylate histones
Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Mean platelet volume (
27863252
)
Metabolite levels (
23823483
)
Natriuretic peptide levels (
21273288
)
Pulse pressure (
30224653
)
Schizophrenia (
23894747
)
Urinary albumin excretion (
32277301
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
60 interacting genes:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CDCA8
CDK8
CHUK
DDB2
DNMT3L
EHMT2
ELP3
EP300
HDGFL2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
NAP1L4
NASP
NCOA6
NRDC
NSD2
PHF21A
PIM1
PKN1
PRMT6
PTMA
PWWP3A
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
17 interacting genes:
CASP8
CEP126
CEP70
DISC1
FEZ1
FEZ2
H2AX
H3C14
HMBOX1
MAGEA11
PICK1
RUBCN
SS18L1
TFIP11
VIM
ZNF512B
ZRANB1
Entrez ID
126961
23774
HPRD ID
11822
06848
Ensembl ID
ENSG00000203811
ENSG00000100425
Uniprot IDs
Q71DI3
A0A024R4V5
A0A024R4W4
O95696
Q59G93
PDB IDs
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
5B0Y
5B0Z
5B40
5BO0
5CIU
5VAC
6ACE
6FML
6T79
6T7A
6T7B
6T7C
6T7D
6X59
6X5A
6XJD
6Y5D
6Y5E
7BQZ
7BU9
7JO9
7JOA
2KU3
2L43
2LQ6
3LYI
3RCW
4Z02
5AME
5AMF
5FG6
5GK9
5N49
5PNX
5PNY
5PNZ
5PO0
5PO1
5PO2
5PO3
5PO4
5PO5
5PO6
5PO7
5PO8
5PO9
5POA
5POB
5POC
5POD
5POE
5POF
5POG
5POH
5POI
5POJ
5POK
5POL
5POM
5PON
5POO
5POP
5POQ
5POR
5POS
5POT
5POU
5POV
5POW
5POX
5POY
5POZ
5PP0
5PP1
5PP2
5PP3
5PP4
5PP5
5PP6
5PP7
5PP8
5PP9
5PPA
5PPB
5PPC
5PPD
5PPE
5PPF
5PPG
5PPH
5PPI
5PPJ
5PPK
5PPL
5PPM
5PPN
5PPO
5PPP
5PPQ
5PPR
5PPS
5PPT
5PPU
5PPV
5PPW
5PPX
5PPY
5PPZ
5PQ0
5PQ1
5PQ2
5PQ3
5PQ4
5PQ5
5PQ6
5PQ7
5PQ8
5PQ9
5PQA
5PQB
5PQC
5PQD
5PQE
5PQF
5PQG
5PQH
5PQI
5PQJ
5PQK
5PQL
5PQM
5PQN
5PQO
5PQP
5PQQ
5PQR
5PQS
5PQT
5PQU
5PQV
5PQW
5PQX
5PQY
5PQZ
5PR0
5PR1
5PR2
5PR4
5PR5
5PR6
5PR7
5PR8
5PR9
5PRA
5PRB
5PRD
5PRE
5PRF
5PRG
5PRH
5PRI
5PRJ
5PRK
5PRL
5PRM
5PRO
5PRP
5PRQ
5PRR
5PRS
5PRT
5PRU
5PRV
5PRW
5PRX
5PRY
5PRZ
5PS0
5PS1
5PS2
5PS3
5PS4
5PS5
5PS6
5PS7
5PS8
5PS9
5PSA
5PSB
5PSC
5PSD
5PSE
5PSF
5PSG
5PSH
5PSI
5PSJ
5PSK
5PSL
5PSM
5PSN
5PSO
5PSP
5PSQ
5PSR
5PSS
5PST
5PSU
5PSV
5PSW
5PSX
5PSY
5PSZ
5PT0
5PT1
5PT2
5PT3
5PT4
5PT5
5PT6
5PT7
5PT8
5PT9
5PTA
5PTB
5PTC
5PTE
5PTF
5PTG
5PTH
5PTJ
5PTK
5PTL
5PTM
5PTN
5PTO
5PTQ
5PTR
5PTS
5PTT
5PTU
5PTV
5PTW
5PTX
5PTY
5PTZ
5PU0
5PU1
5PU2
5PU3
5PU4
5PU5
5PU6
5PU7
5PU8
5PU9
5PUA
5PUB
5PUC
5PUD
5PUE
5PUF
5PUG
5PUH
5PUI
5PUJ
5PUK
5PUL
5PUM
5PUN
5PUO
5PUP
5PUQ
5PUR
5PUS
5PUT
5PUU
5PUV
5PUW
5PUX
5PUY
5PUZ
5PV0
5PV1
5PV2
5PV3
5PV4
5PV5
5PV6
5PV7
5PV8
5PV9
5PVA
5PVB
5PVC
5PVD
5PVE
5PVF
5PVG
5PVH
5PVI
5PVJ
5PVK
5PVL
5PVM
5PVN
5PVO
5PVP
5PVQ
5PVR
5PVS
5PVT
5PVU
5PVV
5PVW
5PVX
5PVY
5PVZ
5PW0
5PW1
5PW2
5PW3
5PW4
5PW5
5PW6
5PW7
5PW8
5PW9
5PWA
5PWB
6IN2
6MAJ
6MAK
Enriched GO Terms of Interacting Partners
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